Shingles Complications and Treatment of Zoster

When Shingles Gets Worse

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Herpes Zoster Virus Lives in Nerves or Dermatomes - Alfred Blaschko
Herpes Zoster Virus Lives in Nerves or Dermatomes - Alfred Blaschko
Shingles may cause complications, including postherpetic neuropathy (PHN), herpes zoster opthalmicus (affecting the eye), staph infections, or disseminated shingles.

People over the age of 50 are particularly at risk for developing a shingles infection. Most of those infections clear without complications, but several problems may occur. These complications may be life-altering, cause chronic pain or disabilities, and may even be life-threatening.

Postherpetic Neuralgia After a Shingles Infection

Shingles pain that persists after the initial rash clears may result in a diagnosis of postherpetic neuralgia (PHN). The Center for Disease Control and Prevention (CDC) web site mentions that this persistent nerve pain may continue for weeks, months, or years and seems to be particularly prevalent in older adults over the age of 60, affecting this age group as much as 50% when a shingles infection occurs. Read the PHN article for more information regarding this complication of shingles.

Shingles Affects the Eye

According to Scott Fraser’s 2008 article in Pulse entitled “Chronic eye conditions,” the shingles virus may affect the upper trigeminal nerve division and cause a painful rash on one side of the face while affecting the cornea of the eye. Herpes zoster opthalmicus results from eye involvement of the shingles and may result in permanent eye damage and even blindness. Hutchinson’s sign suggests an increased likelihood of more severe ocular involvement if the rash extends down the side to the tip of the nose. Symptoms on the face, particularly in and around the eye, calling for immediate attention include:

  • Reddened areas
  • Drainage
  • Difficulty seeing or blurred vision
  • Swollen eyelid
  • Pain

Shingles on the face may also cause ear pain and affect hearing, taste, or balance. The facial muscles may be affected, resulting in Ramsay Hunt syndrome.

According to a 2000 article in Opthalmology Times by Lynda Charters and Alan Palestine entitled “Famcyclovir an option for ophthalmic zoster," Famcyclovir may reduce symptoms of herpes zoster opthalmicus, particularly if started early in the progression of the infection. This article indicates that famcyclovir is more effective than acyclovir in treating herpes zoster opthalmicus.

Bacterial Infection Resulting From a Shingles Infection

According to the CDC, a superinfection of bacteria may occur at the site of the rash. Staphylococcus aureus (“staph”) infections are most common. These infections may leave open sores which may cause skin discoloration and scars. According to the National Institute of Allergy and Infectious Diseases (NIH) web article "Shingles," rare cases of bacterial infection may lead to toxic shock syndrome and necrotizing fasciitis. The NIH web site offers several pictures of shingles infections and information regarding this viral infection and its complications.

Disseminated Shingles

Disseminated shingles affects multiple body systems and generally only occurs in those whose immune system is not functioning properly due to certain conditions, including HIV infection, or because of immune-altering treatments, such as certain types of chemotherapy. The rash spreads over a much larger portion of the body and multiple internal organs, joints, the brain, spinal cord, and nerves may be affected.

The NIH web site mentions that people with disseminated shingles require more intensive hospital care and require more strict isolation procedures, including airborne in addition to standard and contact precautions. Healthcare providers entering rooms of these patients will generally wear gloves, gowns, and masks.

Hope for Lessening or Preventing Shingles Complications

The shingles vaccine offers hope to prevent or lessen cases of the shingles and possible complications, including PHN, eye involvement, bacterial infections, and severe disseminated shingles. Antiviral therapy that is initiated quickly may also minimize shingles and its complications.

Information in this article is not intended to be medical advice. Contact your healthcare provider regarding specific healthcare concerns.

Katrena Wells, Photo by Cyndi Allison, All Rights Reserved

Katrena Wells - Katrena Wells is a RN in NC with 17 1/2 years of experience in oncology, an educator since 1995, and has taught exercise classes since ...

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Comments

Aug 26, 2009 5:30 PM
Cyndi Allison :
Excellent info. Tks.
Aug 26, 2009 6:51 PM
Katrena Wells :
Thanks, Cyndi!
Jul 25, 2010 8:20 PM
Guest :
Very helpful information.Presented clearly which is what the lay person needs to make informed decisions.
Jul 25, 2010 9:49 PM
Katrena Wells :
Thanks so much for reading my article on Shingles Complications and posting such a positive comment. I'm glad you found information that was helpful.
Oct 31, 2010 7:21 PM
Guest :
Very well written and informative. Thank you!
Oct 31, 2010 7:45 PM
Katrena Wells :
Thanks for the positive feedback on my article about zoster or shingles complications. Many people have had or will have a case of the shingles, and I think it can help to know more about this painful condition.
Dec 29, 2010 8:49 AM
Guest :
I am a person with a compromised immune system and I really appreciate any clarity on "disseminated shingles" because I am trying (with the help of an infectious disease specialist) to get to the heart of my condition. There is so little true information out there on patients with conditions like mine. Thank you.
Dec 29, 2010 8:54 AM
Katrena Wells :
Thanks for taking the time to post a comment on my article about shingles complications. Disseminated shingles is not very common, but as you well know, it can happen fairly frequently in people with impaired immunity. I think complications may be harder to find on the internet because much of what is available uses a lot of medical terminology. I am glad you are finding helpful information in my article and hope you won't have a personal cause to search for other health problems, but I welcome anyone reading any of my articles!

By the way, I hope you will have a full recovery.
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